Personal Pronouns in Czech grammar are essential for expressing who is performing an action in a sentence and are typically found replacing a noun or a noun phrase. Czech personal pronouns include já (I), ty (you, singular), on/ona/ono (he/she/it), my (we), vy (you, plural), and oni/ony/ona (they, masculine/feminine/neuter). It is important to note that, in Czech, personal pronouns can change their form based on case, gender, and number; therefore, mastering them is crucial for understanding and usage in everyday conversation.